Breakthrough Lung & Respiratory Updates: COPD Approval, Asthma Gains, TB Milestone & More! 🫁💊
In under 5 minutes, catch up on this week’s biggest headlines in lung and respiratory medicine—featuring game-changing approvals, clinical trial results, and pipeline progress that could redefine care for millions of patients worldwide
🧪 Historic Approval: Dupixent becomes the first-ever biologic approved for COPD in Japan, backed by powerful data from the BOREAS and NOTUS trials.
🫀 Pulmonary Arterial Hypertension Breakthrough: WINREVAIR reduces combined risks by 76 percent in the ZENITH trial—leading to early trial termination due to overwhelming efficacy.
💉 COVID-19 Prevention Progress: Shionogi submits ensitrelvir (Xocova) to the FDA as a first-of-its-kind oral post-exposure prophylactic treatment.
🌬️ Asthma Relief in Sight: Rademikibart shows a rapid 420 mL FEV1 gain in eosinophilic asthma, sustained over 24 weeks with no serious adverse events.
🧬 IPF Therapy Advancement: GRI-0621 shows early safety and tolerability in a first-in-human study—topline data expected in Q3 2025.
🧪 TB Innovation from Rwanda: AKG-100 completes its first cohort in a Phase 1 trial—this novel liposomal formulation could enhance compliance and lower toxicity in TB therapy.
🌫️ Inhaled Antifibrotics: Avalyn’s AP02, an inhaled version of nintedanib, advances to Phase 2 trials, delivering targeted therapy directly to IPF-affected lungs.
📢 Stay Ahead in Lung and Respiratory Health Research!
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